ebv infection การใช้

• Heterophile antibodies can arise in non-EBV infections.
• EBV infection has been specifically associated with nasopharyngeal cancer.
• The plasmablasts do not show rearranged immunoglobulin genes, and typically lack EBV infection.
• However, valid laboratory evidence for continued active EBV infection is seldom found in these patients.
• When such an illness lasts more than 6 months, it is frequently called chronic EBV infection.
• It is important to note that symptoms related to infectious mononucleosis caused by EBV infection seldom last for more than 4 months.
• Straus discovered that infection with EBV very occasionally results in a life-threatening chronic progressive disease, now called chronic active EBV infection.
• EBV infection induces the production of several antibody classes, of which heterophile antibodies are one ( others include anti-i, rheumatoid factor and ANA ).
• EBV infection membrane protein 1 ( LMP1 ) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors.
• :: : Unfortunately, there is no mention of any attempt to determine whether having the rash improves or worsens the patient's recovery from mononucleosis or other EBV infection, which I'd think it well might.
• One participant who was randomized to the placebo arm also had similar rises in C-peptide and dead autoreactive T cells after unexpectedly developing an acute infection with the Epstein-Barr virus; it, like the BCG vaccination, is known to induce TNF . Faustman et al . concluded that BCG treatment or EBV infection transiently modified the autoimmunity that underlies advanced type 1 diabetes.
• EGCG, a polyphenol in green tea, has shown in a study to inhibit EBV spontaneous lytic infection at the DNA, gene transcription and protein levels in a time and dose-dependent manner; the expression of EBV lytic genes Zta, Rta, and early antigen complex EA-D ( induced by Rta ), however, the highly stable EBNA-1 gene found across all stages of EBV infection is unaffected.